Grants
Northwestern Memorial Hospital (September 2020)
Children’s Cancer Institute – $100,000 (September 2020)
The Hospital for Sick Children – $100,000 (September 2020)
Methionine Deprivation as a Therapeutic Strategy for Diffuse Intinsic Pontine Glioma.
Grant InformationHunter Medical Research Institute – $145,640 (September 2020)
Cincinnati Children’s Hospital – $862,671 (May 2020)
International Diffuse Intrinsic Pontine Glioma (DIPG)/Diffuse Midline Glioma (DMG) Registry And Repository
Sydney Children’s Hospital – $151,468 (December 2019)
University of Sydney – $100,000 (November 2019)
Targeting hypoxia and mitochondrial metabolism with repurposing drugs as an approach of radiosensitization for diffuse intrinsic pontine gliomas.
Grant InformationInstitute of Cancer Research – $121,863 (November 2019)
Dayton Children’s Hospital – $69,600 (November 2019)
Responses of distinct cell populations to PDGFRA inhibitors in diffuse intrinsic pontine glioma.
Grant InformationThank You Letter
University of Michigan Hospitals – $157,856 (October 2019)
Telethon Kids Institute – $49,512 (August 2019)
Development of a new and effective therapy against Diffuse Intrinsic Pontine Glioma.
Grant InformationInstitute of Cancer Research – $106,647 (October 2018)
Institute of Cancer Research – $100,000 (October 2018)
Short-pulse Ultrasound Delivery of Panobinostat for the Treatment of Diffuse Intrinsic Gliomas in Children
Grant Information
Sydney Children’s Hospital – $175,089 (October 2018)
Polyamine Pathway Metabolism as a Novel Therapeutic Option for Diffuse Intrinsic Pontine Glioma
Grant InformationThank You Letter
Cincinnati Children’s Hospital – $540,742 (November 2018)
Bambino Gesu Children’s Hospital – $99,382 (November 2018)
Ann & Robert H. Lurie Children’s Hospital of Chicago – $35,000 (November 2018)
Stanford University – $200,000 (December 2017)
The Hospital for Sick Children – $162,828 (December 2017)
Targeting DIPG through pharmacological activation of mitochondrial biogenesis: an in vitro and in vivo preclinical study
Grant InformationChildren’s Cancer Institute – $185,706 (December 2017)
Developing novel combination therapeutic approaches for DIPG targeting Polo-like Kinase 1
Grant InformationThank You Letter
The Campbell Family Institute for Cancer Research – $100,000 (December 2017)
Defining the molecular mechanisms of DIPG development and progression to uncover novel therapeutic targets
Grant InformationOspedale Pediatrico Bambino Gesu – $98,987.89 (December 2017)
Investigating the role of DIPG-derived exosomes in tumor growth and invasion
Grant InformationThank You Letter
The Hospital for Sick Children – $100,560 (December 2017)
MRI Guided Focused Ultrasound: Towards Clinical Translation in Diffuse Intrinsic Pontine Glioma (DIPG
Grant InformationAnschutz Medical Campus – $50,000 (December 2017)
Toward a Multimodality Cure for DIPG: Investigation of Intratumoral Drug Penetration and Craniospinal Irradiation
Grant InformationChildren’s National Medical Center – $200,000 (October 2017)
Validation of TAK228 as an Effective Drug for Treating Children Diagnosed with DIPG.
Grant InformationTexas Children’s Hospital and Ann & Robert H. Lurie Children’s Hospital of Chicago – $200,000 (October 2017)
Targeting DIPG through Combining a Super-activator (MCB-613) of Steroid
Receptor Co-activators with Radiation:
an in vivo Study in Patient-derived Intra-brain Stem Xenograft Models
Gustave Roussy – $101,868 (October 2017)
Elucidating the underlying mechanisms of radioresistance at diagnosis and
relapse in DIPG
Institute of Cancer Research – $102,432 (October 2017)
Massachusetts General Hospital – $50,000 (October 2017)
University of California San Francisco – $70,000 (October 2017)
An Open Label Single Arm Phase I/II study of MTX110 delivered by convection-enhanced delivery (CED) in patients with diffuse intrinsic pontine glioma (DIPG) previously treated with external beam radiation therapy
Dr. Mueller Awarded $70,000 for DIPG Research
Grant InformationThank You Letter
Memorial Sloan Kettering Cancer Center – $100,000 (October 2017)
Dr. Phillips Awarded $100,000 for DIPG Research
Targeting EZH2 as a therapeutic strategy in DIPG
Grant InformationAnn & Robert H. Lurie Children’s Hospital – $100,000 (October 2017)
Dr. Becher Awarded $100,000 for DIPG Research
Determine the efficacy of BMP and MEK inhibitors with RT to treat ACVR1 mutant DIPG
Grant InformationDana Farber Cancer Institute – $100,000 (October 2017)
Defining the Cellular Architecture of Diffuse Intrinsic Pontine Glioma through Large-Scale Single-cell RNA-sequencing analyses
Grant InformationThank You Letter
University of Massachusetts Medical School – $50,000 (May 2017)
Children’s Cancer Institute – $143,884 (September 2016)
Radiosensitisation of Diffuse Intrinsic Pontine Gliomas by modulating the glucose metabolism
Grant InformationThank You Letter
Cold Spring Harbor Laboratory – $100,000 (September 2016)
The Hospital for Sick Children – $194,260 (September 2016)
Gustave Roussy Cancer Center – $46,535.50 (September 2016)
UCL Institute of Child Health – $200,000 (December 2015)
Boston Children’s Hospital – $110,000 (December 2015)
Children’s National Health System and Children’s Research Institute – $125,000 (December 2015)
Comprehensive Molecular‐Based Cross‐Species Comparison of DIPG Biology
Grant InformationThank You Letter
Baylor College of Medicine/Texas Children’s Hospital – $200,000 (December 2015)
Targeting DIPGs through Super-activation of Steroid Receptor Co-activators: An in vivo Study in Patient-derived Intra-brain Stem Xenograft Mouse Models
Grant InformationMemorial Sloan Kettering Cancer Center – $99,880 (October 2015)
Sequential phase I studies of nivolumab monotherapy and nivolumab in combination with ipilimumab in pediatric patients with relapsed or refractory CNS tumors
Grant InformationCincinnati Children’s Hospital Medical Center – $100,000 (December 2015)
An early Phase 2 Study of LEE011, a CDK4/6 Inhibitor, following radiation therapy in Children with Newly Diagnosed non-biopsied Diffuse Pontine Gliomas (DIPG) and Rb+ biopsied DIPG and High Grade Gliomas (HGG)
Grant InformationThank You Letter
Dana-Farber Cancer Institute – $100,000 (December 2015)
Characterizing resistance mechanisms to radiation therapy and adjuvant chemotherapy in
Diffuse Intrinsic Pontine Glioma
Thank You Letter
Dana-Farber Cancer Institute – $100,000 (October 2015)
Discovering novel epigenetic dependencies in Diffuse Intrinsic Pontine Glioma
Grant InformationThank You Letter
Children’s Cancer Institute – $145,341 (November 2015)
Fenretinide, a novel agent targeting RTK/PI3K/AKT network for the treatment of Diffuse Intrinsic Pontine Glioma.
Grant InformationThank You Letter
VU University Medical Center – $92,950 (November 2015)
Liquid Biopsies for the Monitoring of Diffuse Intrinsic Pontine Glioma.
Grant InformationThank You Letter
Children’s National Hospital – $200,000 (October 2015)
Sick Kids Hospital – $190,905 (October 2015)
Mitochondrial DNA alterations and their potential as a novel therapeutic target in DIPG
Grant InformationCincinnati Children’s – $200,000 (October 2015)
Intra-tumoral heterogeneity in diffuse intrinsic pontine and midline high-grade gliomas
Grant InformationThank You Letter
Stanford University – $200,000 (September 2015)
Institute of Cancer Research – $99,470 (September 2015)
European DIPG Registry – $932,917.50 (September 2015)
International DIPG Registry – $699,935 (August 2015)
Stanford University – $50,000 (May 2015)
Tumor Associated Microglia in Diffuse Intrinsic Pontine Glioma
Cincinnati Children’s Hospital – $176,186 (November 2014)
DIPG Registry
University of California, San Francisco – $100,000 (September 2014)
Single-cell profiling and targeting of developmentally regulated signaling programs in DIPG
Grant InformationThank You Letter
VU University Medical Center – $30,529.68 (September 2014)
The Institute of Cancer Research – $95,325 (September 2014)
The Hospital for Sick Children – $99,400 (September 2014)
Dana-Farber Cancer Institute – $50,000 (December 2013)
Cincinnati Children’s Hospital Medical Center – $205,000 (November 2013)
Establishment of an International Diffuse Intrinsic Pontine Glioma (DIPG) Registry
Grant InformationThank You Letter
Yale University School of Medicine – $100,000 (November 2013)
The Hospital for Sick Children – $100,000 (November 2013)
Duke Children’s Hospital – $85,394 (November 2013)
Development of peptide vaccine for diffuse intrinsic pontine glioma
Grant InformationThank You Letter
Texas Children’s Cancer Center – $100,000 (November 2013)
Targeting DIPGs in vivo in Intra-brain Stem Xenograft Mouse Models through Combined Radiation and Oncolytic Viral Therapy
Grant InformationThank You Letter
Monash Institute of Medical Research – $108,840 (AU) (November 2013)
Children’s Hospital of Chicago – $100,000 (November 2013)
Ex-vivo expanded natural killer (NK) cells to target DIPG tumor cells in pre-clinical studies
Grant InformationThank You Letter
Children’s National Medical Center – $99,979 (October 2013)
Children’s Cancer Institute Australia – $100,000 (January 2013)
Research of treatments for Diffuse Intrinsic Pontine Glioma (DIPG)
Thank You LetterSt. Jude Children’s Research Hospital – $15,000 (November 2012)
Establishment and Characterization of Renewable Tissue Resources for Diffuse Intrinsic Pontine Glioma Research
Grant Information
Thank You Letter
Texas Children’s Cancer and Hematology Services – $100,000 (November 2012)
Preclinical Evaluation of Novel BMI—1 Inhibitors in vivo in Intra—Brainstem Orthotopic Xenograft Mouse Models
Grant InformationThank You Letter
Cincinnati Children’s Hospital Medical Center – $219,000 (January 2012)
Texas Children’s Hospital – $100,000 (November 2011)
Eliminating Therapy–Resistant Diffuse Intrinsic Pontine Gliomas with Oncolytic Picorna Virus SVV-001: an in vivo Study in Intra-brain Stem Xenograft Mouse Models
Grant InformationThank You Letter
Duke Children’s Hospital & Health Center – $82,049 (November 2011)
Preclinical evaluation of systemic and direct delivery of a PDGFR-alpha antibody
Grant InformationThank You Letter
Doernbecher Children’s Hospital – $100,000 (November 2011)
Rapid Preclinical Development of a Targeted Therapy Combination for DIPG
Grant InformationThank You Letter
Sydney Children’s Hospital – $100,000 (August 2011)
Robotic screening for novel therapies for diffuse pontine gliomas
Grant InformationThank You Letter
